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Abstract #51845 Published in IGR 14-4
Vogt-Koyanagi-Harada disease in Thailand
Yodmuang T; Rothova A; Kunavisarut P; Pathanapitoon KOcular Immunology and Inflammation 2012; 20: 419-422
PURPOSE: To determine clinical characteristics and rate of ocular complications in patients with Vogt-Koyanagi-Harada disease (VKH). METHODS: The authors performed a retrospective review of 48 consecutive patients (92 affected eyes) diagnosed with VKH. Demographic data, clinical manifestations, treatment modalities, and ocular complications were registered. RESULTS: VKH constituted approximately 10% of all new encounters of uveitis patients. Ocular complications developed in 49/92 (53%) eyes. The most frequent complication was cataract (45%), followed by glaucoma (29%). The presence of ocular complications was not associated with stage of the disease at presentation (p = .654) or the treatment modalities (p = .261). Recurrent inflammation developed in 13% and was not associated with initial intravenous corticosteroids or use of immunosuppressive drugs (p = .614 and p = 1.000). CONCLUSIONS: Cataract and glaucoma represented the common ocular complications of VKH. Recurrences developed solely in 13% of patients and were not associated with a specific treatment regimen but with an early withdrawal of systemic corticosteroids.
Department of Ophthalmology, Chiang Mai University, Chiang Mai, Thailand.
Full articleClassification:
9.4.6 Glaucomas associated with inflammation, uveitis (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders)
