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PURPOSE: To study the significance of temporal peripapillary atrophy in the pathogenesis of open-angle glaucoma in its early stage. Cases and METHOD: Sterometry of temporal peripapillary atrophy was performed in 46 eyes of 46 patients with early-stage open-angle glaucoma and in 38 eyes of 38 healthy persons using a Heidelberg Retina Tomograph. RESULTS: The area of peripapillary atrophy averaged 0.78 ? 0.46 mm? in glaucoma eyes and 0.55 ? 0.33 mm? in controls. The difference was significant (p<0.002). Its volume averaged 0.04 ? 0.04 mm3 in glaucoma eyes and 0.02 ? 0.02 mm3 in controls. The difference was significant (p<0.001). Both the area and volume of disc cupping were significantly greater in glaucoma eyes than in controls (p<0.001). The volume of rim of the disc was significantly smaller in eyes with symmetrical cupping than asymmetrical one (p<0.001). Both the area and volume of peripapillary atrophy were significantly greater in eyes with asymmetrical cupping than symmetrical one (p<0.001 each). CONCLUSION: The presence, shape and size of temporal peripapillary atrophy are closely associated with the pathogenesis of open-angle glaucoma in its early stage. (Japanese)
Yoshikawa Eye Clinic, Nakamachi Machida; Japan
2.12 Choroid, peripapillary choroid, peripapillary atrophy (Part of: 2 Anatomical structures in glaucoma)