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Abstract #52079 Published in IGR 14-4
Detection of glaucoma in a cohort of chinese subjects with systemic hypertension
Gangwani RA; Chan J; Lee J; Kwong A; Lai JSJournal of Ophthalmology 2013; 2013: 463710
PURPOSE: To determine the presence and type of glaucoma in a cohort of adult Chinese subjects with systemic hypertension. METHODS: This prospective cohort study included 200 hypertensive Chinese adults aged >40 years old who underwent screening via frequency doubling technology (FDT) perimetry and intraocular pressure (IOP) measurement by noncontact tonometry (NCT) in a general outpatient clinic. Those with IOP > 21 mmHg and/or visual field (VF) defects on FDT were referred for complete ophthalmological examination. The diagnosis of glaucoma was based on an abnormal VF on Humphrey Field Analyzer (HFA) by Hodapp-Parrish-Anderson's criteria and an increased vertical cup-disc ratio (VCDR). RESULTS: The mean age of the subjects was 64.66 ± 9.47 years, and the male:female ratio was 92 : 108. All patients were hypertensive with a mean blood pressure (BP) of 131.1 ± 15.1/76.6 ± 11.1 mmHg whilst on systemic antihypertensive medication. Of the 111 patients that had an abnormal initial screening, 14 (7.9%) were confirmed to have glaucoma with the highest prevalence of normal tension glaucoma (NTG) (6.2%), followed by primary angle closure glaucoma (PACG) (1.1%) and primary open angle glaucoma (POAG) (0.5%). The positive predictive value of FDT perimetry was 71%. CONCLUSION: Nearly 8% of the adults with systemic hypertension had glaucoma, and NTG was the most prevalent type.
Department of Ophthalmology, The University of Hong Kong, Hong Kong.
Full articleClassification:
1.6 Prevention and screening (Part of: 1 General aspects)