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Abstract #5211 Published in IGR 1-2
Thickness of retinal nerve fiber layer in early-stage glaucoma
Takahashi I; Tanaka MJapanese Journal of Clinical Ophthalmology 1999; 53: 1363-1366
In order to obtain findings in early-stage glaucoma, we measured the thickness of retinal nerve fiber layer using a Nerve Fiber Analyzer GDx (TM). The cases comprised 50 eyes of 38 patients with early-stage glaucoma with impaired visual field, 22 eyes of 16 patients with glaucoma with advanced visual field defect and 20 eyes of 11 age-matched healthy persons as control. Out of 15 parameters, eyes with advanced glaucoma showed significantly abnormal values in 12 parameters as compared with control. Abnormal value (p < 0.05) in more than one parameter was detected in 82% of eyes with early-stage glaucoma, of wh ich only 2 parameters were significant as compared with the control, namely, deviation from normal in the inferior quadrant and inferior average. The specificity and sensitivity for all the glaucoma eyes were 80% and 78% respectively. The sensitivity for early-stage glaucoma was 72%. These findings show that the current method is not adequate in detecting early-stage glauoma.
I. Takahashi, Department of Ophthalmology, Juntendo University Urayasu Hospital, 2-1-1 Tomioka, Urayasu-shi 279-0021; Japan
Classification:
2.13 Retina and retinal nerve fibre layer (Part of: 2 Anatomical structures in glaucoma)
6.9.1 Laser scanning (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis)
