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Abstract #5336 Published in IGR 1-2
Effect of systemic nilvadipine on preventing progression of visual field defect in normal-tension glaucoma
Yamazaki Y; Hayamizu F; Tanaka CJapanese Journal of Clinical Ophthalmology 1999; 53: 729-733
We performed a prospective study on the effect of nilvadipine, a calcium antagonist, on the visual field in 10 eyes of 10 patients with normal- tension glaucoma (NTG). Another series of 10 eyes of 10 patients with NTG served as control. Both group showed similar features regarding age, refraction, visual field defect and topical antiglaucoma medications. The visual field was assessed using the mean retinal sensitivity by Program 30-2 of Humphrey Field Analyzer. After 2 years of nilvadipine at the daily dose of 4 mg, the treated group showed improved mean retinal sensitivity as compared with the control group. The difference was significant (p = 0.005). No significant difference was present between the two groups regarding intraocular pressure, mean blood pressure, heart rate, and intraocular perfusion pressure. These findings show the efficacy of oral nilvapidine on the visual function in NTG eyes.LA: Japanese
Y. Yamazaki, Department of Ophthalmology, Nihon University School of Medicine, 30-1 Oyaguchikami-machi Itabashi-ku, Tokyo 173-8610; Japan
Classification:
9.2.4 Normal pressure glaucoma (Part of: 9 Clinical forms of glaucomas > 9.2 Primary open angle glaucomas)
11.7 Treatment of bloodflow (Part of: 11 Medical treatment)
