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BACKGROUND: The aim of this study was to assess the effect of goniosynechialysis on intraocular pressure (IOP) and glaucoma medication requirement in patients with angle closure DESIGN: A retrospective chart review PARTICIPANTS: 51 eyes from 42 patients were included in the study. 17 had documented evidence of acute angle closure while 34 had chronic angle closure. METHODS: Examination of the medical records of consecutive patients with synechial primary angle closure who underwent combined phacoemulsification and goniosynechialysis from 2003- 2011 at 3 centres. MAIN OUTCOME MEASURES: IOP and requirement for IOP lowering drops were the main outcome measures RESULTS: Mean follow-up was 25.9 months for the acute group and 25.4 months for the chronic group. Mean preoperative IOP was 23.3 ± 14.4mmHg on an average of 2.5 ± 1.3 glaucoma medications. Mean postoperative IOP was lowered to 13.7 ± 2.4 (p=<0.01) and medication usage was significantly lowered to 0.6 ± 0.9 (p=<0.01). Subjects with documented acute symptomatic angle closure had higher preoperative IOP and a larger IOP fall post GSL (from 30.4mmHg ± 23mmHg to 12.1mmHg ± 2.3mmHg ) compared to those without such a documented episode (19.8 mmHg ± 4.4mmHg to 14.4mmHg ± 2.1mmHg, p=0.007). Both groups have similar post op need for glaucoma medication, 0.7± 0.9 vs 0.7 ± 0.9. CONCLUSIONS: Combined phacoemulsification and goniosynechialysis reduces IOP, medication requirements and need for further surgery in subjects with angle closure. The procedure is more effective in eyes with a previously documented acute symptomatic presentation of angle closure.
Centre for Vision Research, Department of Ophthalmology and Westmead Millenium Institute, University of Sydney, NSW, Australia.
Full article9.3.5 Primary angle closure (Part of: 9 Clinical forms of glaucomas > 9.3 Primary angle closure glaucomas)
12.14.3 Phacoemulsification (Part of: 12 Surgical treatment > 12.14 Combined cataract extraction and glaucoma surgery)