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Abstract #53691 Published in IGR 15-2
Orbital Invasion by ACTH-Secreting Pituitary Adenomas
Dhaliwal JS; Seibold LK; Kleinschmidt-Demasters BK; Lillehei KO; Hink EM; Prall JA; Durairaj VDOphthalmic Plastic and Reconstructive Surgery 2014; 30: e28-e30
Orbital invasion by pituitary tumors is rare. To the best of the authors' knowledge, adrenocorticotrophin (ACTH)-secreting pituitary tumors with orbital invasion have not been described in MEDLINE indexed literature. The authors report 2 cases of ACTH-secreting tumors with orbital invasion. One patient had a history of endoscopic transsphenoidal subtotal resection of an ACTH-secreting tumor and presented with recurrence in the orbit. The second patient had a long history of visual loss considered to be secondary to glaucoma. Neuroimaging revealed a destructive mass involving the sella turcica with extension in the right orbit. Debulking of the mass was performed via a transsphenoidal approach, and histopathology revealed an ACTH-secreting adenoma. ACTH-secreting adenoma should be considered in the differential of tumors involving the sella turcica with orbital invasion.
*University of Colorado School of Medicine, Aurora, Colorado, U.S.A.; †Department of Ophthalmology, University of Colorado Eye Center, Aurora, Colorado, U.S.A.; ‡Department of Neurosurgery, School of Medicine, University of Colorado Denver, Aurora, Colorado, U.S.A; and §South Denver Neurosurgery, Denver, Colorado, U.S.A.
Full articleClassification:
10 Differential diagnosis e.g. anterior and posterior ischemic optic neuropathy
