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Abstract #53802 Published in IGR 15-2
Features of optic disc progression in patients with ocular hypertension and early glaucoma
Lloyd MJ; Mansberger SL; Fortune BA; Nguyen H; Torres R; Demirel S; Gardiner SK; Johnson CA; Cioffi GAJournal of Glaucoma 2013; 22: 343-348
PURPOSE: To determine the clinical features of optic disc progression in patients with ocular hypertension and early glaucoma. PATIENTS: A total of 336 eyes of 168 patients with ocular hypertension or early glaucoma. METHODS: Two glaucoma specialists independently graded the baseline and most recent optic disc photographs for optic disc progression. Optic disc progression was defined as: new or increased neuroretinal rim thinning (2 or more clock hours), notching (1 clock hour or less of thinning of the neuroretinal rim), excavation (undermining of the neuroretinal rim or disc margin), and nerve fiber layer defect(s). They also determined the location of these changes. RESULTS: Ninety-two of 336 eyes (27.4%) showed optic disc progression after a median of 6.1 years. Of those with progression, excavation occurred in 89% of eyes; rim thinning occurring in 54%; and notching occurring in 16%. Fifty-six percent (56%) had 2 or more features of progression. The inferotemporal quadrant was the most common location for progression, but more than 1 location of progression occurred in at least 30% of eyes with progression. CONCLUSIONS: Optic disc progression occurred frequently in this cohort of ocular hypertension and early glaucoma patients. When evaluating the optic disc for glaucomatous progression, eye care providers should pay particular attention to increased excavation and neuroretinal rim thinning-especially in the inferotemporal quadrant.
Devers Eye Institute, Portland, OR 97210, USA.
Full articleClassification:
6.20 Progression (Part of: 6 Clinical examination methods)
2.14 Optic disc (Part of: 2 Anatomical structures in glaucoma)
9.2.1 Ocular hypertension (Part of: 9 Clinical forms of glaucomas > 9.2 Primary open angle glaucomas)
