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Abstract #53834 Published in IGR 15-2
Low cerebrospinal fluid pressure in the pathogenesis of primary open-angle glaucoma: epiphenomenon or causal relationship? The Beijing Intracranial and Intraocular Pressure (iCOP) study
Wang N; Jonas JBJournal of Glaucoma 2013; 22: S11-2
Previous experimental and clinical investigations have suggested that some patients with primary open-angle glaucoma may have an abnormally low orbital cerebrospinal fluid pressure (CSFP). A meta-analysis of available clinical data showed a marked overlap in lumbar CSFP measurements between patients with normal-tension glaucoma and healthy subjects, so that the question arises as to which additional factors play a role in the pathogenesis of glaucomatous optic neuropathy.
Department of Ophthalmology, Beijing Tongren Eye Center, Beijing Institute of Ophthalmology, Beijing, China.
Full articleClassification:
9.2.4 Normal pressure glaucoma (Part of: 9 Clinical forms of glaucomas > 9.2 Primary open angle glaucomas)
3.9 Pathophysiology (Part of: 3 Laboratory methods)
2.16 Chiasma and retrochiasmal central nervous system (Part of: 2 Anatomical structures in glaucoma)