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Abstract #54622 Published in IGR 15-3
Abiotrophia defectiva Bleb-associated Endophthalmitis Confirmed With 16S Ribosomal RNA Sequencing
Hugo Lee MH; Lawlor M; Lee AJJournal of Glaucoma 2015; 24: 87-88
One recognized complication of trabeculectomy with visually devastating potential is blebitis. We present a case of a 74-year-old woman with a culture and polymerase chain reaction-positive Abiotrophia defectiva bleb-associated endophthalmitis. Abiotrophia defectiva is a rare but possible cause of endophthalmitis secondary to blebitis and should be considered in culture-negative cases. Prompt identification, hence directed eradication, of the causative organism in such visually threatening cases may be facilitated by requesting polymerase chain reaction and 16S ribosomal RNA sequencing.
*University of New South Wales †Department of Ophthalmology, Liverpool Hospital, Liverpool §Glaucoma Unit, Sydney Eye Hospital, Sydney, NSW, Australia ‡Moorfields Eye Hospital, London, UK.
Full articleClassification:
12.8.11 Complications, endophthalmitis (Part of: 12 Surgical treatment > 12.8 Filtering surgery)
3.5 Molecular biology incl. SiRNA (Part of: 3 Laboratory methods)