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Miscellaneous (17)

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Abstract #54829 Published in IGR 15-3

Level of tear endothelin-1 and plasminogen in patients with glaucoma and proliferative diabetic retinopathy

Pavlenko TA; Chesnokova NB; Davydova HG; Okhotsimskaia TD; Beznos OV; Grigor'ev AV
Vestnik Oftalmologii 2013; 129: 20-23

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A considerable tear endothelin-1 increase (2-3 times) has been found in patients with primary open-angle glaucoma and proliferative diabetic retinopathy. Patients with proliferative retinopathy also showed an increase of plasminogen level in tear fluid and a tendency of a similar increase in blood serum. No correlation between endothelin-1 and plasminogen levels in these pathologies was established. Tear endothelin-1 and plasminogen measurement could be used as an informative and non-invasive method to help prognosis making, condition severity evaluation and control the effectiveness of treatment of ocular local microcirculatory disturbances.

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Classification:

15 Miscellaneous
3.7 Biochemistry (Part of: 3 Laboratory methods)

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