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Abstract #5522 Published in IGR 1-2
Die Zyklokryokoagulation in der behandlung therapierefraktarer glaukome: eine retrospektive analyse von 185 zyklokryokoagulationen (Cyclocryotherapy for the treatment of advanced chronic glaucoma: An analysis of 185 cyclocryotherapies)
Nicaeus T; Derse M; Schlote T; Erb C; Rohrbach JM; Thiel H-JKlinische Monatsblätter für Augenheilkunde 1999; 214: 224-230
BACKGROUND: For several years it has been discussed whether cyclocryotherapy is still an up-to-date treatment of resistant inadequately controlled glaucoma. This retrospective study investigates the clinical aspects of 185 cyclocryotherapies between 1988 and 1997. PATIENTS AND METHODS: At the University Eye Clinic of Tubingen, 114 patients received in 119 eyes (643%) one cyclocryotherapy, and in 66 eyes (35.7%) multiple cyclocryotherapies. The standard surgical techniques for cyclocryotherapy can be summarized as followed: probe placements per eye, 4 to 6; location of probe placement, inferior circumference (63.9%); distance of the applicator from limbus, 3 mm (50.7%); temperature of the probe tip, -70 degree C (34.2%); and time of the treatment, 60 seconds (89.9%). RESULTS: Intraocular pressure was on average 33.8 mmHg before treatment. In all analysed glaucoma types intraocular pressure was lowered to 10.2 mmHg (30%). The most frequent type of glaucoma was the neovascular glaucoma (55%). One year after treatment, this type showed on average, relative to all other types of glaucoma, the highest intraocular pressure (28.1 mmHg) and a lowering of intraocular pressure by 8.3 mmHg (22.7%). Half a year after cyclocryotherapy, a highly significant (p < 0.002) reduction of antiglaucomatous medication was achieved in comparison to the preoperative medication. CONCLUSION: Despite the fact that cyclocryotherapy is not always effective, it is an ambulant surgical technique easy to apply, non-invasive, cost-effective and can be repeated to lower intraocular pressure in resistant chronic glaucoma. We conclude that cyclocryotherapy will remain usefull until new techniques, like the diode laser cyclophototherapy (especially ultrasonic controlled), are developed as alternative therapies.
T. Nicaeus, Augenklin. E.-Karls-Univ. Tubingen, Abt. I (Allg. Augenheilk. Poliklin.), Universitat-Augenklinik Tubingen, Schleichstr. 10-12, D-72076 Tubingen; Germany
Classification:
12.10 Cyclodestruction (Part of: 12 Surgical treatment)
