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Abstract #5649 Published in IGR 2-1
Clinical investigation: Quantitative analysis of visual field and optic disk in glaucoma: retinal nerve fiber bundle-associated analysis
Jünemann GM; Martus P; Wisse M; Jonas JGraefe's Archive for Clinical and Experimental Ophthalmology 2000; 238: 306-314
BACKGROUND: A study was performed to evaluate whether visual field analysis using a perimetric nerve fiber bundle map gives information additional to global visual field indices and cumulative defect curves for early glaucoma diagnosis. METHODS: One hundred and four control subjects, 124 patients with ocular hypertension (OHT), 97 patients with high-tension glaucoma without visual field defects (preHTG), and 91 patients with open-angle glaucoma with visual field defects (30 low-tension glaucoma (LTG), 61 high-tension glaucoma (HTG)) were included in this study. Correlation analyses were performed between (a) global visual field indices and total neuroretinal rim (NRR) area; (b) local mean values of four visual field areas and the NRR area of the corresponding four optic disc sectors; and (c) local mean values of ten perimetric nerve fiber bundles (PNFB1-10) according to Weber and Ulrich (1991) and the four optic disc sectors. The correlations were adjusted for global mean defect and total NRR. RESULTS: There were no significant correlations between NRR area and visual field in control subjects or in patients with OHT or preHTG for all three analyses. Significant correlations were found between the global visual field indices and the total NRR area for LTG and HTG. Significant correlations between local mean defects and NRR area of corresponding optic disc sectors were found only in LTG for the superior and inferior visual field area and the PNFB covering these areas. CONCLUSIONS: The method used for visual field analysis and sectorization of the optic disc does not give additional information on visual field defects in patients with normal global visual field indices and a normal cumulative defect curve. The nerve fiber bundle-related visual field analysis allows the topographical determination and quantification of glaucomatous damage.
Dr. G.M. Jünemann, Department of Ophthalmology, University Erlangen-Nürnberg, Schwabachanlage 6, 91054 Erlangen, Germany. email: anselm.juenemann@augen.med.uni-erlangen.de
Classification:
6.6.2 Automated (Part of: 6 Clinical examination methods > 6.6 Visual field examination and other visual function tests)
6.8.2 Posterior segment (Part of: 6 Clinical examination methods > 6.8 Photography)
