advertisement
Abstract #5681 Published in IGR 2-1
Pulsatile ocular blood flow in patients with pseudoexfoliation
Mistlberger A; Gruchmann M; Hitzl W; Sitte S; Grabner GSpektrum der Augenheilkunde 2000; 14:14-18
Pseudoexfoliation syndrome (PEX) is one of the most frequently diagnosed causes of open-angle glaucoma and has been shown to be statistically significantly associated with a high risk of hypertension, angina, myocardial infarction or stroke, and retinal vein thrombosis. The aim of this study was to evaluate the pulsatile ocular blood flow (POBF) in PEX with and without glaucoma. Eleven eyes with PEX without glaucoma, 11 with a diagnosis of PEX-glaucoma, and seven normal eyes of age-matched controls were enrolled. A complete ophthalmological examination included measuring the POBF with the Langham pneumotonometer as well as the determination of the nerve fiber layer thickness by scanning laser polarimetry (GDx(TM)). There was no difference for the blood flow parameters, pulse amplitude, pulse volume or POBF between the groups (p>0.004). A negative correlation between the intraocular pressure and the POBF was found for all eyes. Out of the GDx(TM) parameters analyzed 'ellipse modulation' was significantly correlated to POBF. Measurements of the POBF are an additional option for the diagnosis and follow-up of glaucoma. However, none of the parameters that are measured by the POBF showed a correlation with the presence of pseudoexfoliation. LA: German
Dr. A. Mistlberger, Landesklinik Augenheilkunde/Optometrie, Sankt Johanns-Spital, Mullner Hauptstrasse 48, A-5020 Salzburg, Austria
Classification:
6.11 Bloodflow measurements (Part of: 6 Clinical examination methods)
9.4.4.1 Exfoliation syndrome (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders > 9.4.4 Glaucomas associated with disorders of the lens)
