Abstract (IGR: 2-1) | International Glaucoma Review #

Abstract #5712 Published in IGR 2-1

Visual field losses in subjects with migraine headaches

McKendrick AM; Vingrys AJ; Badcock DR; Heywood JT
Investigative Ophthalmology and Visual Science 2000; 41: 1239-1247

PURPOSE: To characterize the visual fields of subjects with migraine headaches using static and temporal modulation perimetry. METHODS: Sixteen subjects with migraines (15 with aura, one without) and 15 nonheadache controls were tested. Perimetry was conducted seven days after the offset of a headache with both static and temporally modulated targets, using the Medmont M-600 automated perimeter (Medmont Pty Ltd, Camberwell, Victoria, Australia). Flicker thresholds were measured using the autoflicker test, which varies flicker rate with eccentricity. A subset of four subjects with migraines (three with aura, one without) had the temporal tuning characteristics of their loss evaluated using fixed temporal frequencies (4, 6, 9, 12, and 16 Hz). RESULTS: Field losses were identified with temporal modulation perimetry in 11 of 16 migraine subjects. The majority of these losses occurred in the presence of normal static thresholds (8/11). The deficits displayed temporal tuning, being greatest for higher temporal frequencies (9 Hz). None of the subjects revealed deficits typical of cortical lesions. The migraine-without-aura subject displayed a selective loss to temporally modulated stimuli, which was consistent with the aura group. This defect altered over time, decreasing for 30 to 40 days, but remaining, to a smaller extent, for up to 75 days after the headache event. CONCLUSIONS: Visual dysfunction that is selective for temporally modulated targets occurs in migraine subjects. The migrainous pattern of dysfunction shares some features with that identified in early stages of glaucoma, and raises the possibility of a common precortical vascular involvement in these two conditions.

Dr. A.J. Vingrys, Department of Optometry and Vision Sciences, University of Melbourne, Corner of Cardigan and Keppel Streets, Cariton 3053, Victoria, Australia. a.vingrys@optometry.unimelb.edu.au

Classification:

9.2.2 Other risk factors for glaucoma (Part of: 9 Clinical forms of glaucomas > 9.2 Primary open angle glaucomas)

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