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PURPOSE: The evaluation of frequency and amplitude of IOP elevations in patients after RK who were administrated topically dexamethasone. MATERIAL AND METHODS: RK was carried out in 90 eyes (55 patients). All these patients had been treated topically with 0.1% dexamethasone (Maxitrol, Alcon) since the first day after surgery until three months post-surgery, in decreasing doses. IOP was measured using an air-puff tonometer (Reichert, USA) before surgery and on days 1, 2, 3, 14, 30, 50, 90 after RK. In case of IOP elevation, measurements were taken more often. RESULTS: The mean IOP before surgery was 14.88±2.86 mmHg for females and 16.14±2.83 mmHg for males. In the three months after RK, maximum IOP increased significantly for both females (mean, 21.46±7.51 mmHg) and males (mean, 26.14±8.87 mmHg). An IOP higher than 25 mmHg was observed in 35 eyes (37.7%). These IOP elevations were observed more often in males than in females, but this difference was not statistically significant. There was no correlation between frequency of IOP elevation and preoperative refractive error or age of the patients. CONCLUSIONS: The use of steroids after RK requires careful monitoring of IOP. This subject needs further study to see whether these IOP elevations can damage eye function. LA: Polish
Dr. J.J. Kaluzny, Kliniki Okulistycznej AM w Bydgoszczy
9.4.1 Steroid-induced glaucoma (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders)