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Abstract #5738 Published in IGR 2-1
Electron microscopic study on the development of precapsular layer in eyes with exfoliation syndrome
Zhang X; Khalil AK; Kubota T; Inomata HJapanese Journal of Ophthalmology 2000; 44:9-14
PURPOSE: To search for a pathogenic mechanism for the formation of the precapsular layer on the anterior lens surface in pre-exfoliative eyes. METHODS: The authors examined anterior lens capsules obtained during surgery from 38 patients (16 controls, ten exfoliation suspects, 12 exfoliation) by transmission electron microscopy. RESULTS: A precapsular layer was found in five of 16 controls and in seven of ten exfoliation suspects. It was composed mainly of microfibrils 5-8 nm in diameter. Degenerated zonular fragments were occasionally found interspersed in, and sometimes merged with, microfibrils of the precapsular layer. CONCLUSION: Zonular fibers might contribute to the formation of the precapsular layer in pre-exfoliation stages.
Dr. Z. Zhang, Department of Ophthalmology, Faculty of Medicine, Kyushu University, Fukuoka, Japan
Classification:
9.4.4.1 Exfoliation syndrome (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders > 9.4.4 Glaucomas associated with disorders of the lens)