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Abstract #57395 Published in IGR 16-2
Transcorneal electrical stimulation in patients with primary open angle glaucoma : A pilot study
Röck T; Naycheva L; Willmann G; Schatz A; Wilhelm B; Peters T; Zrenner E; Bartz-Schmidt KU; Gekeler FOphthalmologe 2014; 0:
BACKGROUND: Recently, reports have been published on the effectiveness of electrical stimulation in patients and experimental animal models with neurodegenerative ocular disease. PATIENTS AND METHODS: Our study included 14 patients with primary open angle glaucoma (POAG), who were randomized into one of three groups with 0 % (sham, n = 5), 66 % (n = 5) or 150 % (n = 4) of the individual electrically stimulated phosphene threshold. Patients were treated with transcorneal electrical stimulation (TES) for 30 min once a week for 6 consecutive weeks. Outcome measures of our study were the detection of possible adverse events as well as efficacy of TES with DTL electrodes in subjective and objective parameters of visual function under therapy. RESULTS: Toleration of TES was good. The development of an optic disc hemorrhage in a sham-stimulated eye was recorded as the only adverse event. CONCLUSION: In summary, there were no statistically significant differences shown with all methods of investigation in intraindividual changes to the baseline examination between the groups. It was shown that TES with DTL electrodes does not trigger adverse or serious adverse events in the stimulated groups in patients with POAG.
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