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Abstract #5773 Published in IGR 2-1

Which patients are treated for glaucoma? An observational analysis

Bohn RL; Gurwitz JH; Yeomans SM; Glynn RJ; Pasquale LR; Walker AM; Avorn J
Journal of Glaucoma 2000; 9:38-44


PURPOSE: More than one million patients in the USA are treated for glaucoma, although little is known about the typical clinical characteristics of this group of patients and the type of therapy they receive. This study was conducted to describe the demographic and diagnostic characteristics of patients beginning long-term drug therapy for glaucoma. METHODS: This cross-sectional study included 544 patients beginning topical glaucoma medication regimens who received care at a group model health-maintenance organization (HMO) located in central Massachusetts. The primary medical records of 544 patients beginning topical glaucoma medication between 1987 and 1990 were reviewed to ascertain the presence of three clinical findings: intraocular pressure (IOP) > or = 22 mmHg; optic disc changes including cup-to-disc ratio > or = 0.8, cup-to-disc asymmetry > or = 0.2, or morphological disc changes consistent with glaucomatous optic neuropathy; and visual field defect consistent with glaucoma. RESULTS: The majority of the 544 patients (86%) were diagnosed as having primary open-angle glaucoma (POAG) by their physicians. Almost half (44.7%) these patients only had an elevation in IOP without other clinical findings, and 9% met none of the above criteria for glaucoma according to information in the medical record. CONCLUSION: In this setting, most patients who were prescribed drug therapy for POAG were treated for an elevation in IOP alone in the absence of other ophthalmological characteristics of glaucoma.

Dr. R.L. Bohn, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA


Classification:

11.1 General management, indication (Part of: 11 Medical treatment)



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