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Abstract #5787 Published in IGR 2-1
A comparison of the effectiveness of dorzolamide and acetazolamide in preventing-postoperative intraocular pressure rise following phacoemulsification
Chakraborty P; Villada JR; Tinu ATJournal of the Royal College of Surgeons of Edinburgh 1999; 44/6:411-412
in this letter to the editor the corresponding authors comment on a paper by Zohdy et al on the effectiveness of dorzolamide and acetazolamide in preventing post-operative pressure rise following phacoemulsification.They disagree with the original authors. They present there own randomized masked and placebo controled study. It compared Acetazolamide 250 mg and topical apraclonidine. They concluded that oral acetozolamide was superior to apraconidine. In another study acetazolamide was find to be more effective then apraclonidine. Based on their experience with apraclonidine they conclude that oral acetazolamide is more appropriate then topical medications for the prevention of pressure peaks after surgery and they evidently also include dorzolamide in their conclusion although they did not study it. the original authors come up with reasons why thier conclusion is correct. They are of a methodological order. They still feel that dorzolamide is as good as acetazolamide.
Classification:
11.3.3 Apraclonidine, brimonidine (Part of: 11 Medical treatment > 11.3 Adrenergic drugs)
11.5 Carbonic anhydrase inhibitors (Part of: 11 Medical treatment)
12.12.3 Phacoemulsification (Part of: 12 Surgical treatment > 12.12 Cataract extraction)
