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Abstract #5841 Published in IGR 2-1

Use of polyunsatured fatty acids in the treatment of glaucomatous optic neuropathy (GON)

Caramazza N; Damele M; Parente G; Alessandrini A; Cellini M
Annali di Ottalmologia e Clinica Oculistica 1999; 125:329-338


This study was performed to evaluate the therapeutic effectiveness of the association of polyunsatured fatty acids in the treatment of glaucomatous optic neuropathy (GON). Sixty patients affected by chronic open-angle glaucoma were submitted to color Doppler imaging (CDI), visual field (VF) and contrast sensitivity (CS). Then they were randomly divided into two groups. One group was given a daily association of polyunsatured fatty acids, the other one a placebo. After three months of treatment, in the patients treated with polyunsatured fatty acids, the authors observed significant improvement in visual field and contrast sensitivity, and even more interestingly, a significant improvement of blood flow at the posterior ciliary arteries by CDI. This results suggest that polyunsatured fatty acids, acting on nervous cell trophism, contribute to preserve nervous fiber functioning in glaucomatous optic neuropathy. LA: Italian

Dr. N. Caramazza, University of Bologna, Department of Ophthalmology, Bologna, Italy


Classification:

11.15 Other drugs in relation to glaucoma (Part of: 11 Medical treatment)



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