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Abstract #5851 Published in IGR 2-1
Membrane formation in the chamber angle after failure of argon laser trabeculoplasty: analysis of risk factors
Koller T; Stürmer J; Reme C; Gloor BBritish Journal of Ophthalmology 2000; 84:48-53
AIM: Membrane formation in the chamber angle induced by argon laser trabeculoplasty (ALT) can be a cause of treatment failure. Identification of risk factors for membrane formation was the primary aim of this retrospective study. METHODS: Semithin sections of trabeculectomy specimens obtained in a two-year period were examined by light microscopy. One hundred and twenty-two eyes which were treated with one or more ALTs before trabeculectomy were identified. In 46 eyes, a sufficient amount of trabecular meshwork was obtained to permit morphological analysis. RESULTS: Eyes treated with ALT had a significantly higher incidence of membrane formation (p=0.001). In 23/46 specimens, a cellular and collagenous membrane was observed covering the entire trabecular meshwork. In 14/23 specimens (61%), this membrane was readily visible at low power magnification (x40). Comparison of these eyes with those without membrane formation revealed a significant difference in the number of ALTs (mean 2.07 (SD 0.73) versus 1.48 (0.59); p=0.026) and in preoperative IOP (32.0 (9. 7) versus 26.2 (8.4) mmHg; p=0.04). CONCLUSIONS: Membrane formation in the chamber angle is a frequent cause of ALT failure. The major risk factor is the number of ALTs performed.
Dr. T. Koller, Augenklinik, Universitätsspital, Zürich, Switzerland
Classification:
12.4 Laser trabeculoplasty and other laser treatment of the angle (Part of: 12 Surgical treatment)
