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Abstract #58793 Published in IGR 16-3
The effect of oral propranolol on intraocular pressure in infants with Sturge-Weber syndrome glaucoma
Wygnanski-Jaffe T; Spierer A; Melamed S; Ben-Zion IEuropean Journal of Ophthalmology 2014; 0: 0
PURPOSE: To report the effect of oral propranolol on intraocular pressure (IOP) in infants newly diagnosed with unilateral Sturge-Weber syndrome (SWS) glaucoma receiving no other treatment. METHODS: This was a prospective, nonrandomized interventional case series. Four infants presenting with unilateral SWS glaucoma with no prior treatment were treated with oral propranolol at a dose of 2 mg/kg and followed thereafter. RESULTS: Propranolol had a temporary IOP-lowering effect in 3 of 4 children after 1 week of treatment. This effect diminished thereafter and 3 of 4 children required additional medical or surgical treatment. CONCLUSIONS: Oral propranolol has a temporary effect on IOP in SWS glaucoma and is not effective as a single treatment in this syndrome, yet can serve to delay surgical treatment for a short period of time. In one case, the glaucoma was well-controlled on this medication.
The Goldschleger Eye Institute, Sheba Medical Center, Tel Hashomer - Israel.
Full articleClassification:
9.4.15 Glaucoma in relation to systemic disease (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders)
9.1.2 Juvenile glaucoma (Part of: 9 Clinical forms of glaucomas > 9.1 Developmental glaucomas)
11.15 Other drugs in relation to glaucoma (Part of: 11 Medical treatment)
