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Abstract #5904 Published in IGR 2-1
Influence of postoperative topical application of miotics after cataract extraction on intraocular pressure and the blood-aqueous barrier
Tomida I; Martus P; Küchle MOphthalmologe 1999; 96:583-586
BACKGROUND: In the present study the authors evaluated the influence of topical miotics on intraocular pressure and the blood-aqueous barrier after uncomplicated phacoemulsification and PC-IOL implantation. PATIENTS AND METHODS: Fifty-two eyes were randomized into two groups: with miotics (n=28) and without miotics (n=24). The IOP was measured before, six hours, and one and two days after surgery. Measurement of aqueous flare was performed before and on days 1 and 2 after surgery. Patients with glaucoma, PEX or previous intraocular surgery were excluded. RESULTS: In the group without miotics, IOP was 17.9 mmHg (±3.34) six hours postoperatively; in the second group, this was 15.5 mmHg (±3.25); p=0.04. On the first postoperative day, IOP measured in the group without miotics was 15.3 mmHg (±2.70) and with miotics 13.0 mmHg (±2.28); p=0.007. On the second day, in the group without miotics, IOP was 13.9 mmHg (±3.05) and with miotics 12.60 mmHg (±2.19); p=0.53. The changes in aqueous flare on the first and second days after surgery showed no significant influence of miotics on the blood-aqueous barrier (p>0.05). CONCLUSIONS: Immediate postoperative application of topical miotics led to a small yet significant reduction of the IOP during the first 24 hours after surgery. These data suggest that there is no need for pharmacological reduction of IOP after uncomplicated cataract surgery. LA: German
Dr. I. Tomida, Augenklinik mit Poliklinik, Universität Erlangen-Nürnberg, Erlangen, Germany
Classification:
12.12.3 Phacoemulsification (Part of: 12 Surgical treatment > 12.12 Cataract extraction)
