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Abstract #59104 Published in IGR 16-3

Trabecular-iris circumference volume in open angle eyes using swept-source fourier domain anterior segment optical coherence tomography

Rigi M; Blieden LS; Nguyen D; Chuang AZ; Baker LA; Bell NP; Lee DA; Mankiewicz KA; Feldman RM
Journal of Ophthalmology 2014; 2014: 590978

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PURPOSE: To introduce a new anterior segment optical coherence tomography parameter, trabecular-iris circumference volume (TICV), which measures the integrated volume of the peripheral angle, and establish a reference range in normal, open angle eyes. METHODS: One eye of each participant with open angles and a normal anterior segment was imaged using 3D mode by the CASIA SS-1000 (Tomey, Nagoya, Japan). Trabecular-iris space area (TISA) and TICV at 500 and 750 µm were calculated. Analysis of covariance was performed to examine the effect of age and its interaction with spherical equivalent. RESULTS: The study included 100 participants with a mean age of 50 (±15) years (range 20-79). TICV showed a normal distribution with a mean (±SD) value of 4.75 µL (±2.30) for TICV500 and a mean (±SD) value of 8.90 µL (±3.88) for TICV750. Overall, TICV showed an age-related reduction (P = 0.035). In addition, angle volume increased with increased myopia for all age groups, except for those older than 65 years. CONCLUSIONS: This study introduces a new parameter to measure peripheral angle volume, TICV, with age-adjusted normal ranges for open angle eyes. Further investigation is warranted to determine the clinical utility of this new parameter.

Robert Cizik Eye Clinic, 6400 Fannin Street, Suite 1800, Houston, TX 77030, USA.

Full article

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Classification:

6.9.2.1 Anterior (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis > 6.9.2 Optical coherence tomography)
2.4 Anterior chamber angle (Part of: 2 Anatomical structures in glaucoma)

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