advertisement
Abstract #5913 Published in IGR 2-1
Effect of rocuronium compared with succinylcholine on intraocular pressure during rapid sequence induction of anaesthesia
Chiu CL; Jaais F; Wang CYBritish Journal of Anaesthesia 1999; 82:757-760
The authors have compared the effect of rocuronium and succinylcholine on intraocular pressure (IOP) during rapid sequence induction of anesthesia using propofol and fentanyl, in a randomized double-blind study. They studied 30 adult patients, allocated to one of two groups. Anesthesia was induced with fentanyl 2 mg kg-1 and propofol until loss of verbal response. This was followed by succinylcholine 1.5 mg kg-1 (group S; n=15) or rocuronium 0.9 mg kg-1 (group R; n=15). Laryngoscopy was performed 60 seconds later. IOP, mean arterial pressure (MAP), and heart rate (HR) were measured before induction, immediately before intubation and every minute after intubation for five minutes. A Keeler Pulsair air impulse tonometer was used to measure IOP and the mean of two readings obtained in the right eye at each measurement time was recorded. Intubating conditions were evaluated according to a simple scoring system. IOP in the succinylcholine group was significantly greater than that in the rocuronium group (mean 21.6 (SEM 1.4) mmHg versus 13.3 (1.4) mmHg; p < 0.001). Intubating conditions were equally good in both groups. The authors conclude that, with rapid sequence induction of anesthesia using propofol and fentanyl, rocuronium did not cause as great an increase in IOP as succinylcholine and may be an alternative in open eye injury cases.
Dr. C.L. Chiu, Department of Anaesthesia, University of Malaya, Kuala Lumpur, Malaysia
Classification:
12.17 Anesthesia (Part of: 12 Surgical treatment)
