advertisement
Abstract #59206 Published in IGR 16-3
Safety And Efficacy Of Achieving Single-Digit Intraocular Pressure Targets With Filtration Surgery In Eyes With Progressive Normal-Tension Glaucoma
Schultz SK; Iverson SM; Shi W; Greenfield DSJournal of Glaucoma 2016; 25: 217-222
PURPOSE: Whereas achieving intraocular pressure (IOP) targets ≤10 mm Hg typically requires surgical intervention, we sought to examine the safety and efficacy of trabeculectomy in normal-tension glaucoma (NTG). METHODS: Patients with progressive NTG undergoing trabeculectomy with preoperative IOP≤15 mm Hg during the 12-month period before surgery were identified at a single academic institution. Failure was defined as IOP reduction <20% below baseline (criteria A), <30% (criteria B), or <40% (criteria C), reoperation for glaucoma, or loss of light perception vision. RESULTS: Thirty eyes of 28 patients (mean age, 73±8.7 y) were enrolled with a mean follow-up period of 50±31 months. Mean postoperative IOP (8.6±2.9 mm Hg) and medications (0.6±1.0) at final follow-up was significantly (P<0.001) reduced compared with before surgery (13.2±1.4 mm Hg and 2.5±1.2, respectively). The cumulative probability of failure during 5 years of follow-up was 32% (criteria A), 48%, (criteria B), and 67% (criteria C). The probability of successfully achieving an IOP goal ≤10 mm Hg was 68% at 4 years of follow-up. CONCLUSIONS: Trabeculectomy is a safe and effective method for achieving single-digit IOP targets in NTG eyes with progression at low IOP.
Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL.
Full articleClassification:
9.2.4 Normal pressure glaucoma (Part of: 9 Clinical forms of glaucomas > 9.2 Primary open angle glaucomas)
6.20 Progression (Part of: 6 Clinical examination methods)
12.8.1 Without tube implant (Part of: 12 Surgical treatment > 12.8 Filtering surgery)
