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Abstract #59353 Published in IGR 16-3

Corneal Deformation Parameters Provided by the Corvis-ST Pachy-Tonometer in Healthy Subjects and Glaucoma Patients

Salvetat ML; Zeppieri M; Tosoni C; Felletti M; Grasso L; Brusini P
Journal of Glaucoma 2015; 24: 568-574


PURPOSE: To evaluate precision and accuracy of Corvis-ST, a new noncontact tonometer equipped with a high-speed Scheimpflug technology, which measures intraocular pressure (IOP), central corneal thickness (CCT), and corneal deformation parameters (CDPs). Relationships among IOP, CCT, and CDPs were also assessed. MATERIALS AND METHODS: This prospective, randomized study included 1 eye of 164 subjects (79 controls and 85 glaucoma patients), which underwent IOP measurements taken 3 times with Goldmann applanation tonometry (GAT) and Corvis-ST in random order. Precision was evaluated using intraclass correlation coefficients. Intermethod agreement was assessed using Bland-Altman method. Relationships amongst IOP, CCT and CDPs were evaluated using linear regression analysis. RESULTS: Corvis-ST intraclass correlation coefficients ranged between 0.95 and 0.99 for IOP and CCT; between 0.17 and 0.97 for CDPs. Mean (GAT-Corvis-ST) IOP was 1.4±2.7 mm Hg, which appeared related to IOP and CDPs (P<0.05). CDPs significantly differed between glaucoma patients and controls (P<0.05). GAT and Corvis-ST IOP was related to CCT (P<0.05) and CDPs (P<0.001). CONCLUSIONS: Corvis-ST precision was excellent for IOP and CCT; moderate for CDPs. Corvis-ST underestimated GAT IOP, especially at higher IOP and at lower corneal deformability levels. GAT and Corvis-ST IOP increased in thicker and less deformable corneas. Glaucoma patients showed significantly less deformable corneas than controls.

Department of Ophthalmology, Azienda Ospedaliero-Universitaria, "Santa Maria della Misericordia," Udine, Italy.

Full article

Classification:

6.1.1 Devices, techniques (Part of: 6 Clinical examination methods > 6.1 Intraocular pressure measurement; factors affecting IOP)
2.2 Cornea (Part of: 2 Anatomical structures in glaucoma)



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