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Abstract #59561 Published in IGR 16-3

Correlation between the ganglion cell complex and functional measures in glaucoma patients and suspects

Teixeira IC; Bresciani-Battilana E; Barbosa DT; Caixeta-Umbelino C; Paolera MD; Kasahara N
International Ophthalmology 2014; 0:


The purpose of the study was to correlate the Fourier-domain OCT ganglion cell complex (GCC) parameters with automated perimetry (AP) functional measures of the optic nerve. This retrospective study included patients who had previously undergone examination with the RTVue-100 OCT and AP, SITA strategy. The parameters of GCC (average, superior, inferior, S-I [superior inferior difference], S-I SD [standard deviation of S-I], GLV [global loss volume] and FLV [focal loss volume]) were correlated with the mean deviation (MD) and pattern standard deviation (PSD) values of AP using linear and logarithmic regression analysis. All correlations between GCC and automated perimetry parameters were strong (r > 0.60), except that for SI and MD (r = -0.05); SI and PSD (r = 0.09); SI-DS and MD (r = -0.06); and SI-SD and PSD (r = 0.08). In summary, GCC derived structural measures showed good correlation with functional parameters from AP.

Department of Ophthalmology, Irmandade da Santa Casa de Misericordia de Sao Paulo, Santa Casa de Sao Paulo School of Medical Sciences, Rua Sao Mauro, 292, São Paulo, 02526-050, Brazil.

Full article

Classification:

6.9.2.2 Posterior (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis > 6.9.2 Optical coherence tomography)
6.6.2 Automated (Part of: 6 Clinical examination methods > 6.6 Visual field examination and other visual function tests)
2.13 Retina and retinal nerve fibre layer (Part of: 2 Anatomical structures in glaucoma)



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