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Abstract #59563 Published in IGR 16-3
Torsion of the Optic Nerve Head is a Prominent Feature of Normal Tension Glaucoma
Park HY; Lee KI; Lee K; Shin HY; Park CKInvestigative Ophthalmology and Visual Science 2014; 0:
PURPOSE: To compare optic nerve head (ONH) morphology between eyes with normal tension glaucoma (NTG) and primary open angle glaucoma (POAG). METHODS: Seventy eight NTG patients and matched 78 POAG patients according to age and axial length were analyzed. ONH tilt and disc torsion were identified from cross-sectional images of optical coherence tomography. The degree of horizontal, vertical, and maximum ONH tilt and torsion were compared between NTG and POAG eyes and additional comparisons were based on the presence of myopia and the location of the visual field defect. Logistic regression analysis was used to determine the factors related to the degree of ONH torsion. RESULTS: Horizontal (P = 0.610) and vertical tilt degree (P = 0.746) did not differ between NTG and POAG eyes. However, torsion degree (P = 0.022) differed significantly between NTG and POAG eyes. Direction of horizontal tilt (P = 0.040) and torsion (P < 0.001) showed more prevalent superior tilt and torsion in NTG eyes (21.8% and 33.3%, respectively) compared to POAG eyes (10.3% and 10.3%, respectively). Myopic NTG eyes showed greater torsion degree (P = 0.014) than non-myopic NTG eyes, which was not observed in comparison between myopic and non-myopic POAG eyes. Only NTG eyes showed a significant difference in the degree of maximum tilt (P < 0.001) and torsion (P < 0.001) and the direction of horizontal tilt (P < 0.001) and torsion (P = 0.010) by the location of visual field defect. Longer axial length, maximum tilt degree, and diagnosis of NTG were the factors related to the degree of ONH torsion. CONCLUSIONS: NTG eyes had a greater ONH torsion compared to POAG eyes with matched axial length. The direction of the ONH tilt and torsion was related to the location of the visual field defect only in NTG eyes.
Department of Ophthalmology and Visual Science, The Catholic University of Korea, Seoul St. Mary's Hospital, College of Medicine, Seoul, Korea (South), Republic of.
Full articleClassification:
9.2.4 Normal pressure glaucoma (Part of: 9 Clinical forms of glaucomas > 9.2 Primary open angle glaucomas)
2.14 Optic disc (Part of: 2 Anatomical structures in glaucoma)
6.9.2.2 Posterior (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis > 6.9.2 Optical coherence tomography)
