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Abstract #60504 Published in IGR 16-4

Structural alterations during the course of glaucoma disease

Mardin CY; Schlötzer-Schrehardt U
Ophthalmologe 2015; 112: 410-417

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BACKGROUND: Structural changes in the course of glaucoma disease affect the trabecular meshwork and ciliary body in addition to the optic disc as the primary site of glaucoma damage. OBJECTIVES: Latest results from experimental studies, animal models and measurements in human eyes are presented and discussed. RESULTS: The presenting scenario is complex with age, biochemical and mechanical stress factors leading to subsequent, irreversible tissue change in the trabecular meshwork and cribriform plate of the optic nerve, resulting in neuronal tissue loss. CONCLUSION: Knowledge of these changes will be the key for future glaucoma therapies.

Universitätsaugenklinik Erlangen, Schwabachanlage 6, 91054, Erlangen, Deutschland, Christian.Mardin@uk-erlangen.de.

Full article

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Classification:

2.5.1 Trabecular meshwork (Part of: 2 Anatomical structures in glaucoma > 2.5 Meshwork)
2.14 Optic disc (Part of: 2 Anatomical structures in glaucoma)

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