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AIM: The utility of retinal thickness analysis (RTA) in the primary open-angle glaucoma (POAG) early diagnosis and in the follow-up was evaluated. MATERIALS AND METHODS: The nerve fibre layer thickness was analysed with the RTA by repeated examinations in POAG, ocular hypertension (OH) and healthy subjects (H). RESULTS: In the POAG group, a statistically significant reduction of mean retinal thickness (MRT) compared to the H group was evidenced both in the total area examined and in each of the four quadrants. The visual field evaluation classified the POAG group's visual fields in stage 1 and the OH group's visual fields in stage 0. CONCLUSION: RTA reveals a variation of mean retinal thickness, even before a functional and/or morphological optic nerve alteration appears. RTA is a complementary tool with the exams usually applied in the diagnosis of glaucoma, even though the information obtained is not specific for glaucoma.
Department of Sense Organs, Faculty of Medicine and Odontology, Policlinico Umberto I, Sapienza University of Rome, Rome, Italy.
6.9.5 Other (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis)