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Abstract #6237 Published in IGR 2-2
Aqueous dynamics in experimental ab externo trabeculectomy
Rossier A; Uffer S; Mermoud AOphthalmic Research 2000; 32: 165-171
PURPOSE: This study assessed the decrease in intraocular pressure (IOP), the residual outflow resistance of the trabeculum and the filtration site by histology in enucleated pig and human eyes after ab externo trabeculectomy. METHOD: Measurement of the resistance to aqueous outflow was performed using the constant pressure method before and after ab externo trabeculectomy. RESULTS: The outflow facility was 0.31 ± 0.13 μl/min/mmHg in pig eyes and 0.24 ± 0.08 μl/min/mmHg in human eyes before surgery, and 79.0 ± 47. 6 μl/min/mmHg in pig eyes and 6.33 ± 6.67 μl/min/mmHg in human eyes after ab externo trabeculectomy. On histological examination, the aqueous outflow pathway was seen to be at the level of the residual trabecular meshwork. CONCLUSION: This study showed that ab externo trabeculectomy significantly lowers IOP and improves outflow facility in enucleated pig and human eyes.
A. Rossier, Hopital Ophtalmique Jules-Gonin and University of Lausanne, Lausanne, Switzerland
Classification:
12.8.1 Without tube implant (Part of: 12 Surgical treatment > 12.8 Filtering surgery)
