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Abstract #6294 Published in IGR 3-2
Estimated incidence of open-angle glaucoma in Olmsted County, Minnesota
Schoff EO; Hattenhauer MG; Ing HH; Hodge DO; Kennedy RH; Herman DC; Johnson DHOphthalmology 2001; 108: 882-886
PURPOSE: To determine the incidence rates of open-angle glaucoma (OAG) in Olmsted County, Minnesota. DESIGN: A retrospective, population-based, estimate of incidence. PARTICIPANTS: From the medical histories of 60,666 residents of Olmsted County, Minnesota, who had ocular diagnoses during the study period, 114 subjects with newly diagnosed OAG were identified. METHODS: The database of the Rochester Epidemiology Project was used to identify all Olmsted County residents with a coded diagnosis of OAG, glaucoma suspect, or ocular hypertension, during the period 1965 to 1980. Subjects newly diagnosed with, and treated for, OAG, who also had documented clinical evidence of elevated intraocular pressure, optic nerve damage, and/or visual field loss consistent with glaucoma, were included as incident cases. Population data for Olmsted County were drawn from United States Census data. Crude incidence data were adjusted to the age and gender distribution of the 1990 USA white population. MAIN OUTCOME MEASURES: Estimated incidence rates of OAG. RESULTS: The overall age- and gender-adjusted annual incidence rate of OAG in a predominantly Caucasian population is conservatively estimated to be 14.5 per 100,000 population. The rates increased with age from 1.6 in the fourth decade of life to 94.3 in the eighth. There was no significant difference in incidence by gender. The average annual rate of OAG in the last two years of the study was 27.7, compared to 12.3 before 1979. This difference is suggestive of the effect of the introduction of a new medical therapy (timolol) for OAG during the last two years. CONCLUSIONS: The incidence rates of OAG increase markedly with advancing age, and screening efforts should be targeted at both men and women in the older age groups. The advent of new diagnostic and therapeutic modalities can have an effect on incidence rates.
Dr D.H. Johnson, Department of Ophthalmology, Mayo Clinic, 200 First Street SW, Rochester MN 55905, USA
Classification:
1.1 Epidemiology (Part of: 1 General aspects)
