advertisement
Abstract #6335 Published in IGR 3-2
Influence of scan radius correction for ocular magnification and relationship between scan radius with retinal nerve fiber layer thickness measured by optical coherence tomography
Bayraktar S; Bayraktar Z; Yilmaz OFJournal of Glaucoma 2001; 10: 163-169
PURPOSE: To investigate how optical coherence tomography (OCT) modifies the preset scan parameters to correct the errors resulting from ocular magnification, the influence of the examiner's final correction of those already modified parameters on retinal nerve fiber layer (RNFL) thickness measurements, the induced change on RNFL thickness measurements and RNFL estimated integrals (RNFLestimated integrals) by adjusting the actual scan radius during RNFL examinations performed by OCT. METHODS: Thirty-five healthy patients underwent RNFL examination by OCT four times using different scan radii. The first scan was performed with the preset circular scan diameter of 3.46 mm; the actual scan diameter was different, however, because it was modified by the OCT instrument. The second, third, and fourth scans were generated after readjusting the already modified scan diameter by the examiner to 3.46, 3.20, and 3.60 mm. The relationships of axial length and refractive error to the actual scan radius (with ocular magnification calculated by OCT), the influence of the examiner's final correction on RNFL thickness measurements, the relationship between scan radius and RNFL thickness measurements, and RNFLestimated integrals, were investigated. RESULTS: The actual scan diameter was found to be primarily determined by axial length (R = 0.97, p < 0.0001), but the influence of refractive error was small (R = -0.26, p = 0.067). Final correction of the actual scan radius by the examiner had a significant influence on RNFL thickness measurements (p = 0.025). RNFL thickness measurements obtained without correction of the actual scan radius for magnification were found to be inversely correlated with the axial length (R = -0.54, p = 0.001), whereas no similar relationship was found when RNFL thickness measurements were obtained with correction (R = 0.21, p = 0.11). A reciprocal relationship between l/scan radius with RNFL thickness measurements (they tended to be thinner as scan radii were increased) was found (R = 0.21, p = 0.169), but RNFLestimated integrals areas were found to be independent of the scan radius (p = 0.521). CONCLUSIONS: To increase the accuracy of RNFL thickness measurements, it will be appropriate for the examiner to manually correct the actual scan parameters to the desired or preset ones after their automatic modification performed by the OCT instrument. Keeping the actual scan radius constant for repeated examinations is also recommended, because RNFL thickness measurements were found to depend on scan size. Alternatively, RNFLestimated integrals could be used because they were found to be independent of the scan size.
Dr S. Bayraktar, Bankacilar Sok, no. 12/30, Merdivenköy 81080, Istanbul, Turkey
Classification:
2.13 Retina and retinal nerve fibre layer (Part of: 2 Anatomical structures in glaucoma)
6.9.2 Optical coherence tomography (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis)
