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Abstract #6355 Published in IGR 3-2
Frequency doubling technology and confocal scanning ophthalmoscopic optic disc analysis in open-angle glaucoma with hemifield defects
Wu LL; Suzuki Y; Kunimatsu S; Araie M; Iwase A; Tomita GJournal of Glaucoma 2001; 10: 256-260
PURPOSE: To evaluate the potential of frequency doubling technology for detecting early glaucomatous damage. PATIENTS AND METHODS: Forty-nine eyes of 49 patients with open-angle glaucoma with visual field defects in one hemifield only, according to the Humphrey Field Analyzer (HFA) 30-2 program, were included. Forty-five healthy patients were also included as controls. In each patient, frequency doubling technology with the threshold N-30 program and optic disc analysis using the Heidelberg Retina Tomography, was performed. Frequency doubling technology test results and HFA test results were compared. Optic disc parameters corresponding to the hemifield designated intact by the HFA were compared between the eyes in which the hemifield was normal by frequency doubling technology and those in which the hemifield was abnormal. RESULTS: Forty-one percent of the 49 hemifields designated intact by the HFA were abnormal based on frequency doubling technology, whereas 98% of the 49 hemifields designed defective by the HFA were abnormal, and 12% of the 90 hemifields designated intact by the HFA were abnormal in healthy patients. The percentage of hemifields designated abnormal by frequency doubling technology was significantly higher than that in healthy patients (p < 0.001). The rim volume was significantly smaller in eyes with abnormal results based on frequency doubling technology than in eyes with normal results (p < 0.05, paired t test, with Bonferroni correction for multiple comparison). CONCLUSION: Frequency doubling technology can detect glaucomatous damage earlier than conventional static perimetry.
Dr Y. Suzuki, Department of Ophthalmology, University of Tokyo School of Medicine, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan. suzujioph-tky@umin.ac.jp
Classification:
2.14 Optic disc (Part of: 2 Anatomical structures in glaucoma)
6.6.3 Special methods (e.g. color, contrast, SWAP etc.) (Part of: 6 Clinical examination methods > 6.6 Visual field examination and other visual function tests)
6.9.1 Laser scanning (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis)
