advertisement
Abstract #6418 Published in IGR 3-2
An observational, retrospective two-year cost study in primary open-angle glaucoma and ocular hypertension in newly diagnosed patients
Rouland JF; Peigne G; Sellem E; Renard JP; Williamson W; Filippi JM; Cohn H; Hamard P; Abellan P; Chagnon AJournal Français d'Ophtalmologie 2001; 24: 233-243
PURPOSE: To investigate the different treatment strategies in France and the direct costs for patients with newly diagnosed primary open-angle glaucoma (POAG) or ocular hypertension who have started treatment with beta-blockers, and to estimate the total direct cost for two years of treat. MATERIAL AND METHODS: The authors analyzed 225 medical charts retrospective in 11 academically and office-based centers in France over the first two years after diagnosis. Standard costs for each resource in current medical practice were determined from the French Social Security perspective. RESULTS: The vast majority of patients (90%) had a diagnosis of POAG or ocular hypertension in both eyes. In 60% of the patients, a moderate or severe defect was found in their visual field or optic nerve. IOP before treatment was 23.9 ± 4.7 mmHg and 17.5 ± 4.2 mmHg after two years of treatment. Over the first two years, 25% of visits led to a change in therapy (medical or surgical), involving 64% of the patients. Two-thirds of the changes occurred during the first year of treatment and in around 80% of cases for low IOP at check-up. Laser surgery or surgical intervention was performed in 25% of the patients. Total direct costs for two years were FF 5698. The IOP before treatment was positively correlated (p < 0.01) with treatment costs, while the initial IOP effects of treatment were negatively correlated with two-year costs. CONCLUSIONS: After two years of treatment, the mean IOP decreased from 24 to 17.5 mmHg. The higher the basal IOP, the more intensive the treatment and the higher the costs. The more efficient the treatment to decrease baseline IOP, the earlier the costs will be reduced. LA: French
Dr J.F. Rouland, Service d'Ophtalmologie, CHRU, 12, Avenue Oscar Lambret, 59037 Lille Cedex, France
Classification:
9.2.1 Ocular hypertension (Part of: 9 Clinical forms of glaucomas > 9.2 Primary open angle glaucomas)
9.2.3 Open angle glaucoma with elevated IOP (Part of: 9 Clinical forms of glaucomas > 9.2 Primary open angle glaucomas)
11.1 General management, indication (Part of: 11 Medical treatment)
14 Costing studies; pharmacoeconomics
