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PURPOSE: To determine the clinical course of patients with Posner Schlossman syndrome (PSS). DESIGN: A retrospective, noncomparative case series. PARTICIPANTS: Fifty-three eyes of 50 patients. METHODS: The case notes of all patients with PSS seen at the Uveitis Clinic of Singapore National Eye Centre were reviewed for evidence of glaucoma damage and risk factors. MAIN OUTCOME MEASURES: Visual field and optic disc changes consistent with glaucoma. RESULTS: There were 28 males and 22 females, with a mean age at onset of 35 years. Fourteen eyes (26.4%) were diagnosed as having developed glaucoma as a result of repeated attacks of PSS. Patients with ten years or more of PSS have a 2.8 times higher risk (95% confidence interval 1.19-6.52) of developing glaucoma compared with patients with less than ten years' duration of the disease. Nine eyes (17%) underwent glaucoma filtering surgery with antimetabolities; their postoperative follow-up ranged from 15-50 months (mean, 37 months). Four eyes continued to have episodes of iritis after surgery, and one of these had elevated intraocular pressure during the event. CONCLUSIONS: A significant number of patients with PSS has glaucoma develop over time, and they need to have their optic disc appearance and visual fields carefully monitored.
Dr Soon-Phaik Chee, Singapore National Eye Centre, 11 Third Hospital Avenue, Singapore 168751
9.4.6 Glaucomas associated with inflammation, uveitis (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders)