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The authors observed two patients with bilateral optic atrophy secondary to organic solvents. One was a 25-year-old male who had habitually inhaled organic solvents for the preceding five years. His visual acuity was 0.08 right and 0.06 left. Both eyes showed optic atrophy with excavation. The other was a 40-year-old alcohol-dependent male. Sudden visual loss developed immediately after he drank 500 ml methyl alcohol two months earlier. His visual acuity was hand motion in both eyes. Funduscopy showed a swollen and hyperemic disc in the right eye and advanced optic atrophy in the left. Visual acuity decreased to light perception three months later. Both eyes showed advanced optic atrophy with excavation. Scanning laser ophthalmoscopy (SLO) showed normal morphology of the pores of the bared lamina cribrosa. These cases illustrate that toxic atrophy of the optic disc with excavation can be differentiated from glaucomatous optic atrophy based on SLO findings. LA: Japanese
Dr S. Yamamoto, Department of Ophthalmology, Ryukyu University Faculty of Medicine, 207 Uehara Nisihara-cho, Okinawa-ken, 903-0125, Japan
10 Differential diagnosis e.g. anterior and posterior ischemic optic neuropathy