advertisement
Abstract #6487 Published in IGR 3-2
Diurnal fluctuation of intraocular pressure following additional topical latanoprost
Ito K; Kimura Y; Kishi SJapanese Journal of Clinical Ophthalmology 2001; 55: 1167-1170
The evaluated the effect of topical latanoprost in 50 glaucoma eyes of 25 patients. Initially, all the patients had been receiving a beta-blocker instilled twice daily. Latanoprost was added to be instilled once before sleep. After additional use, the intraocular pressure (IOP) significantly decreased both in the morning and afternoon. In 20 primary open-angle glaucoma eyes, there was a more significant rise in IOP in the afternoon than in the morning. After additional use, this rise in the afternoon was suppressed, resulting in no difference in IOP between morning and afternoon. Additional use failed to suppress the rise in IOP in the afternoon in 16 normal-tension glaucoma eyes. Additional use suppressed the rise in IOP in the afternoon in six of neovascular glaucoma eyes. The use of latanoprost in addition to a beta-blocker thus induced lowering of IOP without diurnal fluctuation. LA: Japanese
Dr K. Ito, Department of Ophthalmology, Gunma University School of Medicine, 3-39-22 Showa-machi, Maebashi-shi, Gunma-ken 371-8511, Japan
Classification:
11.4 Prostaglandins (Part of: 11 Medical treatment)
