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Abstract #6560 Published in IGR 3-2
The use of antimetabolites with trabeculectomy: a critical appraisal (editorial)
Spaeth GL; Mutlukan EJournal of Glaucoma 2001; 10: 145-154
PURPOSE: To examine why most ophthalmologists routinely use mitomycin C or 5-fluorouracil (antimetabolites) in association with filtering surgery for glaucoma. METHODS: Critical analysis of seven medical, social, and economic trends. RESULTS: The rapid acceptance of the adjunctive use of antimetabolites at the time of filtration surgery may be explained by reasons other than the anticipated increase in the 'success' of glaucoma surgery. CONCLUSIONS: The use of antimetabolites in conjunction with filtering glaucoma surgery may be at least partially a consequence of changing medical-social-economic factors, rather than solely a desire on the part of physicians to improve the 'success' of glaucoma surgery. This may indicate a need to re-evaluate the proper place of antimetabolites in association with filtration surgery.
Classification:
12.8.10 Woundhealing antifibrosis (Part of: 12 Surgical treatment > 12.8 Filtering surgery)
