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Abstract #6563 Published in IGR 3-2
Autologous blood injection for late-onset filtering bleb leak
Burnstein A; WuDunn D; Jonescu-Cuypers C; Cantor LBAmerican Journal of Ophthalmology 2001; 132: 36-40
PURPOSE: To report the outcomes of autologous blood injections for late-onset filtering bleb leak. METHODS: Retrospective chart review of all eyes that had autologous blood injection(s) for filtering bleb leak occurring at least two months after trabeculectomy. Successful treatment was defined as resolution of the bleb leak and no need for additional glaucoma medications. Failure was defined as a persistent bleb leak, intraocular pressure (IOP) greater than 21 mmHg, or the occurrence of a vision-threatening event related to the procedure. RESULTS: Thirty-two eyes of 31 patients had autologous blood injection for filtering bleb leak, and were followed for a mean of 4.9 months (SD, 9.2; range, 1-37 months). Twenty-three eyes (72%) were outright failures because of persistence of the leak. Nine eyes (28%) had an initially successful outcome, but the success rate decreased over time as bleb leaks recurred in three of the nine eyes at five, six, and 37 months. No patient characteristics correlated with the outcome. Mean IOP increased from pretreatment to final examination (4.5-6.5 mmHg, P = 0.003). Mean logMAR vision remained unchanged from pretreatment to final examination (p = 0.55). Blood seepage into the anterior chamber after autologous blood injection was common but transient. CONCLUSION: Autologous blood injection is of limited success in treating late-onset filtering bleb leak.
Dr D. WuDunn, Department of Ophthalmology, Indiana University, 702 Rotary Circle, Indianapolis, IN 46202, USA. dwudunn@iupui.edu
Classification:
12.8.11 Complications, endophthalmitis (Part of: 12 Surgical treatment > 12.8 Filtering surgery)
