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Abstract #6627 Published in IGR 4-1
Measurement of iris color using computerized image analysis
Takamoto T; Schwartz B; Cantor LB; Hoop JS; Steffens TCurrent Eye Research 2001; 22: 412-419
PURPOSE: To develop a standardized method for measuring from iris photographs, light and dark segments of areas, and densities of iris color. METHODS: Computerized image analysis was used to measure the iris photographs. The reproducibility of this method was studied in 30 normal eyes with three different colored irides: green-brown, blue-grey brown, and yellow-brown. Three photographs were taken of each iris with a slit-lamp camera at three different exposures at baseline. The photographs were repeated with exposure providing for the best reproducibility at 6.5 ± 1.7 months as a first follow-up after baseline and 3.6 ± 0.8 months following the first follow-up visit. At least one measurement was made for each photograph. RESULTS: The mean percent coefficient of variation (standard deviation of triplicate measurements/mean x 100) ranged from 1.0-4.1% for area and density measurements. Furthermore, the range of mean percent differences between baseline and follow-up visits ranged from 1.2-6.3%. CONCLUSION: The authors have developed a standardized method which appears suitable for measuring changes over time in iris color.
Dr. B. Schwartz, Glaucoma Research, Inc., 20 Park Plaza, Boston, MA 02116, USA. glaucomares@dreamcom.net
Classification:
2.8 Iris (Part of: 2 Anatomical structures in glaucoma)
6.8.1 Anterior segment (Part of: 6 Clinical examination methods > 6.8 Photography)
