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Miscellaneous (27)

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Abstract #66345 Published in IGR 17-3

Conjunctival fibrosis following filtering glaucoma surgery

Schlunck G; Meyer-Ter-Vehn T; Klink T; Grehn F
Experimental Eye Research 2016; 142: 76-82

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Despite advances in surgical technique and postoperative care, fibrosis remains the major impediment to a marked reduction of intraocular pressure without the need of additional medication (complete success) following filtering glaucoma surgery. Several aspects specific to filtering surgery may contribute to enhanced fibrosis. Changes in conjunctival tissue structure and composition due to preceding treatments as well as alterations in interstitial fluid flow and content due to aqueous humor efflux may act as important drivers of fibrosis. In light of these pathophysiological considerations, current and possible future strategies to control fibrosis following filtering glaucoma surgery are discussed.

Eye Center, Freiburg University Medical Center, Freiburg, Germany. Electronic address: guenther.schlunck@uniklinik-freiburg.de.

Full article

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Classification:

2.1 Conjunctiva (Part of: 2 Anatomical structures in glaucoma)
11.16 Vehicles, delivery systems, pharmacokinetics, formulation (Part of: 11 Medical treatment)
12.8.10 Woundhealing antifibrosis (Part of: 12 Surgical treatment > 12.8 Filtering surgery)

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