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PURPOSE. To determine the group II phospholipase A2 (PLA2) content of tears in patients with senile cataract or primary open-angle glaucoma (POAG) and to compare this with the PLA2 content of tears in age-matched healthy controls. METHODS: The PLA2 concentration of tears was measured with time-resolved fluoroimmunoassay in 21 patients with senile cataract, 23 patients with POAG, and in 40 healthy controls. RESULTS. The PLA2 content of tears was 38.3 ± 30.1 μg/ml in patients with senile cataract, 32.1 ± 22.3 μg/ml in patients with POAG, and 36.6 ± 31.1 μg/ml in healthy controls. There were no significant differences between the patient and the control groups. CONCLUSIONS: The authors conclude that neither senile cataract nor POAG has any effect on the PLA2 content of tears.
Prof. K.M. Saari, Department of Ophthalmology, University of Turku, Kiinamyllynkatu 4-8, FIN-20520 Turku, Finland
2.20 Other (Part of: 2 Anatomical structures in glaucoma)