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WGA Rescources

Abstract #6663 Published in IGR 4-1

Pectinate ligament dysplasia and narrowing of the iridocorneal angle associated with glaucoma in the English springer spaniel

Bjerkas E; Ekesten B; Farstad W
Veterinary Ophthalmology 2002; 5: 49-54


OBJECTIVE: The aim of the study was to evaluate whether tonometry and gonioscopy could serve as predictors of later glaucoma development in the English springer spaniel, a breed prone to developing primary glaucoma. ANIMALS STUDIED: Gonioscopy was performed on 279 English springer spaniel dogs, 119 males and 160 females, with clinically normal eyes. In addition, 14 dogs, five males and nine females, were examined for glaucoma. RESULTS: A positive relationship between pectinate ligament dysplasia (PLD) and narrowing of the relative width of the ciliary cleft (RWOCC) and also between PLD, RWOCC, and age, was demonstrated. The prevalence of PLD was 25.5%, which is higher than in other breeds reported. A positive association was demonstrated between PLD and glaucoma, as well as between narrowing of the RWOCC and glaucoma. Glaucoma was not observed in dogs with a normal appearance of the iridocorneal angle. English springer spaniels related to dogs with glaucoma show more narrowing of the RWOCC and more PLD than unrelated dogs. CONCLUSIONS: This study demonstrates the positive association between PLD and glaucoma, between narrowing of the iridocorneal angle and glaucoma, and the effect of age on the iridocorneal angle. Mating of dogs with normal iridocorneal angles appears to reduce the presence and degree of abnormal appearance of the iridocorneal angle in the offspring. However, only breeding dogs with normal iridocorneal angles without consideration of their relationship to dogs with glaucoma does not guarantee the prevention of glaucoma in their offspring.

Dr. E. Bjerkas, Norwegian School of Veterinary Science, Department of Small Animal Clinical Sciences, P.O. Box 8146 Dep., N-0033 Oslo, Norway. ellen.bjerkaas@veths.no


Classification:

5 Experimental glaucoma; animal models
9.1.3 Syndromes of Axenfeld, Rieger, Peters, aniridia (Part of: 9 Clinical forms of glaucomas > 9.1 Developmental glaucomas)



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