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Abstract #67291 Published in IGR 17-4
Anterior-Chamber Angle and Axial Length Measurements in Normal Chinese Children
Jin P; Li M; He X; Lu L; Zhu J; Chang TC; Zou HJournal of Glaucoma 2016; 25: 692-697
PURPOSE: To establish the physiological distribution of anterior-chamber angle parameters and axial length (AL) in a randomly sampled cohort of Chinese children. PATIENTS AND METHODS: This was a prospective, cross-sectional study on randomly sampled Chinese children ages 7 to 15 years. Complete ophthalmologic examination was carried out on all participants; anterior-segment parameters and ALs were measured using Fourier-domain optical coherence tomography and automated biometers. Associations between the age, the sex, the refractive error, the iris thickness, the AL, and anterior-chamber depth (ACD) and angle measurements were analyzed using multiple correlation and regression tests. The relationship between the AL and other factors was studied by a linear regression analysis. Only the right eye data were analyzed for statistical purpose. RESULTS: A total of 541 children were enrolled in this study. There were no differences in angle parameters between sexes (P>0.05), but boys had a longer AL (P<0.01). The AL increased logarithmically with age in children (P<0.01, R=0.5552, b=6.18). Although the magnitude of myopia also increased with AL, this association was less robust (P<0.05, R=0.0917, b=-0.88). A multiple regression test indicated that the age and the ACD were independently associated with the increase in angle width (b=0.37 to 0.50 and 0.51 to 0.60, respectively; P<0.001). CONCLUSIONS: All angle measurements increased with age and were positively correlated with the ACD in children 7 to 15 years of age. The AL increased logarithmically with age.
*Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University †Department of Preventative Ophthalmology, Shanghai Eye Hospital, Shanghai Eye Disease Prevention and Treatment Center, Shanghai, China ‡Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miami, FL.
Full articleClassification:
2.4 Anterior chamber angle (Part of: 2 Anatomical structures in glaucoma)
6.9.2.1 Anterior (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis > 6.9.2 Optical coherence tomography)
