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Abstract #6776 Published in IGR 4-1
The contralateral eye in patients with unilateral iridocorneal endothelial syndrome
Liu Z; Zhang M; Chen J; Ye T; Chen L; Huang T; Lin Y; Feng CChinese Journal of Ophthalmology 2002; 38: 16
OBJECTIVE: To study the clinical characteristics of the contralateral eyes of patients with unilateral iridocorneal endothelial syndrome (ICE). METHODS: The clinical characteristics were analyzed retrospectively in the contralateral eyes of 42 cases of unilateral ICE. Of these, 19 patients (19 eyes) received examination of refraction, intraocular pressure (IOP), slit lamp, gonioscopy, and ultrasound biomicroscopy. In 35 cases (35 eyes), the endothelial cell counts of the contralateral eyes were compared with age-matched normal controls using the t test. RESULTS: In the 19 cases of unilateral ICE syndrome, emmetropia or hypermetropia were found in 88.9%; IOP higher than 21 mmHg was present in one case, and anterior depth lower than 2.2 mm was seen in 50.0%. Atrophy or dysplasia of the iris existed in three cases, there was narrowness and/or adhesion of the anterior chamber angle in three cases and pyramidal adhesion under gonioscopy and/or ultrasound biomicroscopy examination in two cases. One case had relative paracentral scotoma on the visual field examination. Systemic disorders, including hepatitis B, diabetes, hyperthyroidism, duodenum ulceration, and hypertension were found in 31.6%. In the 35 patients who underwent an endothelial cell count, the average endothelial cell density of the contralateral eyes was (2593 ± 432.7)/mm2, which was significantly lower than that of the normal controls (2784.9 ± 280.6)/mm2 (t = -2.43; p = 0.019). The hexagonality and coefficient variation of cell size of ICE patients did not differ from that of normal controls. CONCLUSIONS: The contralateral eye in cases diagnosed as unilateral ICE syndrome may be subclinically involved, and therefore it is necessary to pay attention to the contralateral eye, and follow up all patients suffering from ICE syndrome.LA: Chinese
Dr. Z. Liu, Zhongshan Ophthalmic Center, Sun Yat-sen University of Medical Sciences, Guangzhou 510060, China. zuguol@gzsums.edu.cn
Classification:
9.4.2.1 Iridocorneal endothelial syndrome (ICE, incl. irisatrophy) (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders > 9.4.2 Glaucomas associated with disorders of the cornea, conjunctiva, sclera)
