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Travoprost, given qd in the evening, as an esterified PGF2 analogue, is a highly selective potent prostaglandin-F-receptor agonist. It is superior to timolol 0.5% b.i d. (8.0-8.9 mmHg versus 6.3-7.9 mmHg) and at least as effective in lowering the intraocular pressure compared to latanoprost (0.005%) in patients with open-angle glaucoma or ocular hypertension. It is given once daily in the evening. The most frequent reported treatment related adverse event is ocular hyperemia of a predominantly mild to moderate grade. Eyelash changes and iris hyperpigmentation are observed approximately at the same rate as with latanoprost.LA: German
Dr. A. Hommer, Sanatorium Hera, Augenheilkunde, Loblichgasse 14, 1090 Vienna, Austria
11.4 Prostaglandins (Part of: 11 Medical treatment)