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Abstract #6848 Published in IGR 4-1
Ocular vasospasm and calcium channel blockers in glaucoma
Pillunat LE; Bohm AGSpektrum der Augenheilkunde 2002; 16: 2-7
As well as an increased intraocular pressure (IOP) vascular risk, factors such as vasospasm seem to play a major role in the pathogenesis of the glaucomatous disease. A link between vasospasm and glaucoma was shown in normal pressure and high pressure glaucoma patients. During inhalation of a potent vasodilator a subgroup of these patients showed an improvement in visual function and ocular hemodynamics. As calcium channel blockers lead to a vasodilation due to a direct relaxation of the smooth muscle cell, the effect of these substances on glaucoma patients was studied. Treatment with calcium channel blockers showed a similar improvement of visual function and had a beneficial effect on the course of the disease. This seems to be related to an improvement of ocular hemodynamics.LA: German
Dr. L.E. Pillunat, Vorstand der Univ.-Augenklinik, Carl-Gustav-Carus-Universitat, Fetscherstrasse 74, D-01307 Dresden, Germany
Classification:
11.7 Treatment of bloodflow (Part of: 11 Medical treatment)
